Protandim Side Effects Continued
by TeamDixon...the TRUTH | on March 15, 2012
Protandim side effects is not a very accurate title for this article. A more fitting title would be the lack of side effects of Protandim. Most antioxidant products sold are direct antioxidants. In other words they try to fight free radicals on their own. You are familiar with most of these supplements. They are your vitamins A, C, and E. Where Protandim is different is in the attack method. Protandim gets your body to do what it should do naturally and that is produce the enzymes that fight free radicals. Thank goodness for Protandim, because scientists are realizing how little effect our old “so called” antioxidants are having. For the technical folks Protandim sends signals to your body to produce antioxidant enzymes, SOD (superoxide dismutase), and CAT (catalse). Another soldier in this battle you may or may not have heard of – Gluthione. Studies suggest that gluthione is a key component in anti-aging. I can find zero Protandim side effects. Lifevantage makes no claim to cure diseases but some people on the product have some amazing testimonials. Here what Montel Williams has to say.
The evidence is over whelming that there are zero side effects with Protandim. Anyone out there that hears otherwise we want to know. To get specific we want to list another study on the US National Library of Medicine and National Institutes of Health website. For the complete article just click here now.
“Protandim is an antioxidant supplement that consists of five ingredients, namely, ashwagandha, bacopa extract, green tea extract, silymarin, and curcumin, each with known therapeutic properties. Protandim was formulated with the objective of combining multiple phytochemicals at low nontoxic doses to gain synergy among them. A recent clinical study demonstrated the in vivo antioxidant effects of Protandim (S.K. Nelson et al., 2006, Free Radic. Biol. Med. 40, 341-347). The objective of the present study was to determine if the components of Protandim induce heme oxygenase-1 (HO-1) in a synergistic manner in cultured MIN6 cells, a mouse beta-cell line, and in SK-N-MC cells, a human neuroblastoma cell line. When the components of Protandim were tested alone at low doses, curcumin showed minimal induction, whereas the others were unable to induce the HO-1 promoter, assayed by transient transfection. All components together, however, produced a strongly synergistic induction of around three- to ninefold in a dose-dependent manner, greatly exceeding the sum of the parts. Similar findings were obtained for the expression of HO-1 at the mRNA and protein levels. Protandim-mediated HO-1 induction involved the presence of ARE sites in the HO-1 promoter and nuclear translocalization of the transcription factor Nrf2, which binds to ARE sites. The involvement of multiple signaling pathways, including PI3-kinase/Akt, p38MAPK, and PKCdelta, in HO-1 induction seems to be the probable mechanism of synergy between the components of Protandim. There were significant increases in the levels of total glutathione in Protandim-treated cells. These findings suggest that the use of a combination of phytochemicals may be an efficient method for the induction of antioxidant enzymes…”
With all the research I have done Protandim does not have any side effects. The science is a bit over my head but it does seem to say there are no side effects with Protandim. What I do see out of the research is that Protandim helps your body fight off free radicals. We know that is a good thing. I know some Protandim Rep will send me a 90 day supply and then I will give my own testimony. Until then I want to hear from you.